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About Us
The McMackin Lab harnesses MRI and electrophysiological methods such as transcranial magnetic stimulation (TMS), electromyography (EMG), and electroencephalography (EEG) to understand and develop clinically meaningful measurements of neurological diseases, including Amyotrophic Lateral Sclerosis/ Motor Neurone Disease and Huntington's Disease. The Lab also performs research to understand the basic human physiology underpinning the electrophysiology-based measures, to improve the correct understanding and application of these measures.
The McMackin Lab works in close collaboration with the Academic Unit of Neurology and is part of the EXG Research Group, a collaboration of neuroscience, medicine, physiology, bioengineering and mathematics researchers with the common interest of harnessing electrophysiology to tackle neurological diseases.
Lab News
August 2026
Our recent study led by McMackin Lab Alum Séamus O'Sullivan titled "Very low-amplitude muscle activity increases probability of motor evoked potentials in healthy individuals and in amyotrophic lateral sclerosis" was on the cover of Experimental Physiology Volume 111, Issue 8! https://physoc.onlinelibrary.wiley.com/toc/1469445x/2026/111/8
July 2026
McMackin Lab PhD Student Eva Woods attended the MND Association's MND EnCouRage Event in Loughborough this week. Every year, the MND Association brings together early career researchers (ECRs), senior researchers, clinicians, experts, and the MND community for MND EnCouRage UK. MND EnCouRage is a unique event which helps ECRs who have chosen to research MND to build skills, network and collaborate, and give them the opportunity to share their passion and research with members of the MND community.
Congratulations to Dr. Roisin McMackin, PI of the McMackin Lab, who was a recipient of the 2026 FENS-EJN Young Investigator Award. The awards recognise excellent scientific work in any area of neuroscience and outstanding contributions to neuroscience by early career researchers!!
Our Funders
Our work is also supported by prizes from:
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